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It has a 1% dose of pro-repair GHK-Cu and a 1% dose of pro-collagen GHK-Cu
Suggested areas for future study were detailed groups, which include extensive clinical trials evaluating wider cardiovascular disorders and population groups, to work out the appropriate dose and maximum course of treatment to maximize therapeutic effects and minimize unwanted effects and to integrate genetic, lifestyle, and disease severity factors into the study design to understand if these factors might affect treatment
Zhang W, Konopleva M, McQueen T, Schober W, Andreeff M
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Under oxidative stress and induced by excessive ROS generation, Nrf2 is released from its inhibitor Keap1, allowing its translocation into the nucleus (Kasprzak et al., 2020), where it binds to the antioxidant response element (ARE) present in the DNA sequence of numerous antioxidant enzymes like glutathione-S-transferase, -glutamyl cysteine synthetase (glutamate cysteine ligase), heme oxygenase 1, and paraoxonase-1 inducing their transcription, managing the phase II response to oxidative stress (Kasprzak et al., 2020)
